Bioinformatics Specialist

POSITION OVERVIEW:

The lab of Dr. Daniel Durocher (Lunenfeld-Tanenbaum Research Institute) is currently seeking a candidate to fill a position of Bioinformatics Specialist to support its active research program on DNA repair, cell cycle and synthetic lethality. The Durocher lab is a world-class laboratory studying how damaged DNA is repaired, with the greater goal of understanding how its dysregulation contributes to diseases such as cancer. More information about our research can be found at: durocherlab.org.

The candidate will be using computational methods to assist in research investigations in the area of functional genomics relating to cancer biology and therapeutics. The successful candidate will also be central to most research programs in the laboratory where they will assist in data analysis, visualization, and organization.

DUTIES AND RESPONSIBILITIES:

• Execute next-generation sequencing (NGS) data analysis packages, maintain and troubleshoot NGS analytical pipelines, and manage mass data storage and backup.
• Execute CRISPR/Cas9 screen data analysis platforms (MaGeCK, BAGEL, DrugZ, JACKS and others).
• Execute analysis of various sequencing-based methods (for ChIP-seq, Cut&Run, END-seq, scRNA-seq, etc)
• Assist with data visualization, primarily in R and Python
• Assist with data mining methods and support diverse data analysis strategies
• Provide statistics support to research programs
• Maintain or create laboratory databases.
• Maintain or create laboratory websites.

SKILLS/QUALIFICATIONS:

• Minimum of a B.Sc. In Computer Sciences, Molecular Biology, Bioinformatics or related data sciences (e.g. statistics)
• Two years of experience using bioinformatics, computational biology or data mining tools
• Fluency with statistics/biostatistics, data mining, and dimensionality reduction methods.
• Expertise in scientific languages R and Python
• Training in NGS data analysis packages and pipelines preferred but not essential
• Strong initiative to carry out independent research on data analysis problems and excellent problem-solving skills is an asset.
• Ability to work in a diverse and inter-disciplinary environment.
• Excellent written and verbal communication skills.
• Must be a team player, versatile, flexible, and self-motivated with strong communication skills and attention to detail
• Must demonstrate satisfactory work performance and attendance record

In accordance with Institute’s policy and legislated health and safety requirements, employment is conditional upon the verification of credentials, completion of a health review, and demonstrating proof of immunity and vaccination status of vaccine-preventable diseases. All employees and affiliates will follow safe work practices and comply with health and safety policies, procedures, and training. Successful candidates will be required to provide two (2) written reference letters from their former employer(s)/supervisor(s).

To ensure the safety and wellbeing of all our people and patients, Sinai Health has made it a priority to support everyone in getting vaccinated against COVID-19. Consistent with this, our Staff Immunization & Surveillance Policy was recently updated to include the requirement for full vaccination – currently defined as receiving two doses and serving a 14-day waiting period following the second dose – in order to be able to work at Sinai Health. To be compliant with our updated Policy, you must provide proof of dual COVID-19 vaccination, as indicated on the Prospective Immunization and Surveillance Policy Information Sheet, in order to be eligible for employment at Sinai Health. If you believe you are one of the very few people who may require an exemption from vaccination, supporting medical information must be submitted to our Occupational Health department, who will review and assess.

We are a fully committed to fairness and equity in employment and our recruitment and selection practices. We encourage applications from Indigenous peoples, people with disabilities, members of sexual minority groups, members of racialized groups, women and any others who may contribute to the further diversification of our Sinai Health community. Accommodation will be provided in all parts of the hiring process as required under our Access for People with Disabilities policy. Applicants need to make their requirements known in advance.

The Lunenfeld-Tanenbaum Research Institute is a scent sensitive environment, and all members of the community are expected to refrain from wearing or using scented products while visiting or working at the Institute. We also support a barrier-free workplace supported by the Institute’s accessibility plan, accommodation and disability management policies and procedures. Should you require accommodation at any point during the recruitment process, including accessible job postings, please contact the Lunenfeld-Tanenbaum Human Resources Department.

Hours:37.5 hours per week

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